After meeting at a fundraising gala, an aged but wealthy, Caltech donor makes Leonard ponder if he's willing to have sex with her to secure another donation.
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Mrs. Wolowitz ends up in the hospital after Howard tells her he's marrying Bernadette. While there, Leonard stresses over Penny and Priya warming up to one another.
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Penny entices Leonard to meet with a psychiatrist and the results are surprising; Stuart moves out of the Wolowitz house and Howard and Bernadette find themselves at a loss.
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Dealing with an under-the-weather Sheldon is so draining for Penny, Leonard, and the gang, that they decide to treat themselves to a Sheldon-less weekend.
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Sheldon's grandmother, aka Meemaw, visits and there's friction between her and Amy, which intensifies after the elderly woman blurts out a secret about Sheldon.
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Leonard angers the university and the entire physics community when he gives an embarrassing radio interview. Meanwhile, Amy and Bernadette bond over having to hide their success from Sheldon and Howard.
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Amy records Sheldon talking in his sleep and tries to convince him that he has a more laid-back side. Meanwhile, Raj and Stuart compete to win the heart of Bernadette's new co-worker.
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Wolowitz and Sheldon bond over their relationships with their disappointing fathers when they drive to the desert to shoot off a model rocket. Leonard's mom finds a new best friend in Penny, much to Leonard's dismay.
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Sheldon and Raj confide in Bernadette when they can't handle Amy and Howard working together. Penny and Leonard learn new tactics on how to deal with Sheldon and they come from an unlikely source.
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ABOUT
Leonard and Sheldon are brilliant physicists, the kind of ''beautiful minds'' that understand how the universe works. But none of that genius helps them interact with people, especially women. All this begins to change when a free-spirited beauty named Penny moves in next door.
